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- Details for Colistin sulfate
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Colistin sulfate
Category : Food and Feed additives
CAS NO : 1264-72-8 EC NO : 215-034-3 MF : C52H98N16O13 MW : 1155.4339 Specification : 2% 4% 10% Product description : Product name
Colistin sulfate
CAS No.:
1264-72-8
Specification:
2%, 4%, 10%
Principle:
The positive free amino group of the active ingredients is combined with the negative polyphosphate in the cell membrane as well as with nucleic acid to form insoluble compounds, resulting in cell membrane damage, permeability improvement of cell membrane and leakage of intracellular phosphate and nucleic acid to kill bacteria.
Character
It has strong anti-bacteria activity against Gram-negative bacteria.
Low incidence of anti-drug reactions
No drug cross-resistance with other antibiotics.
It can not be particularly absorbed in alimentary tract. It is highly safe and in lack of residue. It is especially manufactured for healthy foods.
It promotes growth and increases feed utilization rate.
Precaution:
1） It can not be mixed with aureomycin, terramycin, zinc bacitracin-colistin premix and olaquindox for feeding use.
2） The dosage used to treat contagious enteritis is doubled to the highest dosage above.
Synonyms : Colistin Sulphate;n-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide sulfate;N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1);N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide;belcomycin; Molecular Structure : 
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