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N-Hydroxyethyl Aniline 122-98-5
Category : Dyestuffs and Pigments
CAS NO : 122-98-5 EC NO : 204-588-1 MF : C8H11NO MW : 137.179 Specification : 99% min Packing : 25kg，50kg 200kg Product description : What is the chemical of N-Hydroxyethyl Aniline ? Appearance: Colorless or pale yellow transparent oily liquid； Assay:99%min by GC； IR Identity: conform to standard； HNMR： conform to standard； carbon spectrum: conform to standard； Water by K. F.:0.5% max or as per the customer’s request； Loss on drying:0.5% max. or as per the customer’s request； ================================================================================ use: Main Uses of N-Hydroxyethyl Aniline Core Intermediate in Dye Industry: Widely used in the synthesis of azo dyes, anthraquinone dyes, and reactive dyes, serving as a key precursor for constructing aniline-based chromophore groups; Organic Synthesis Raw Material: As an aniline derivative, it participates in condensation, alkylation, acylation, and other reactions, used in the preparation of pharmaceutical intermediates, flavors, and functional polymer materials; Synthesis in Pharmaceuticals and Pesticides: Used for synthesizing intermediates of antihistamines, local anesthetics, and certain fungicides; Laboratory Reagent: Used as a standard substance for analytical chemistry and synthetic pathway verification. ============================================================================= The typical synthetic route of N-phenylethanolamine (2-phenylaminoethanol, N - (2-hydroxyethyl) aniline) is the nucleophilic ring opening reaction of aniline with epoxyethane. • Main synthesis route: Aniline+epoxyethane → N-phenylethanolamine (122-98-5), usually carried out under mild heating (60-100 ° C) and solvent-free or inert solvents (such as toluene, ethanol), can be catalyzed by a small amount of base (such as K ₂ CO3), with a yield of about 60-80%. Alternative route: 2-chloroethanol is condensed with aniline in alkaline aqueous solution or alcohol solvent, but the conditions need to be controlled to avoid double alkylation or hydrolysis side reactions, resulting in lower yield and difficult purification. This compound is an amino alcohol intermediate with the molecular formula C ₈ H ₁ NO and the structural formula C ₆ H ₅ - NH CH ₂ - CH ₂ - OH. The ethylene oxide method is commonly used in industry due to its high atom economy and minimal by-products Uses : N-Hydroxyethyl Aniline is mainly used as an organic synthesis intermediate and a dye intermediate. In industrial production, it participates in various organic reactions to prepare chemicals such as dyes and pharmaceuticals. It can also be used as a solve Synonyms : N-hydroxyethylaniline;N-(2-hydroxyethyl)aniline;N-Phenylethanolamine;N-Hydroxyethylamine; Molecular Structure : 
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N-Hydroxyethyl Aniline