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- Region :China/Tianjin
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Fmoc-Met(O2)-OH 163437-14-7
Category : Intermediates/Pharmaceutical intermediates
CAS NO : 163437-14-7 EC NO : MF : C20H21NO6S MW : 403.44 Specification : 99% min Packing : 25kg 50kg drum or bag Product description : What is the chemical of Fmoc-Met(O2)-OH ? Appearance: White powder ; Assay: 99% min by HPLC ; IR Identity: conform to standard ; HNMR： conform to standard ; carbon spectrum: conform to standard ; Water by K. F.:0.5% max or as per the customer’s request ; Loss on drying:0.5% max. or as per the customer’s request ; =============================================================================== Usage: Mainly used in peptide synthesis, as a Fmoc protected methionine sulfone derivative, for introducing modified methionine residues in solid-phase peptide synthesis. In addition, it is also used as an organic synthesis and pharmaceutical intermediate ============================================================================= Synthesis generally involves the following general strategies (based on common knowledge of organic synthesis, not directly provided by data): Starting from L-methionine, sulfide is oxidized to sulfone through selective oxidation (such as using peroxy acid). Perform amino protection reaction between oxidized methionine derivatives and Fmoc Cl (9-fluorenylmethoxycarbonyl chloride) or Fmoc OSu (Fmoc succinimide ester). The final product was obtained through purification. Uses : Mainly used in peptide synthesis, Synonyms : Fmoc-L-methionine-sulfone;Fmoc-L-methionine sulfone; Molecular Structure : 
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Fmoc-Met(O2)-OH