China Suppliers > Tianjin Yuansu Chemical Reagent Co., LTD > Ethyl difluoroacetate
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Ethyl difluoroacetate 454-31-9
Category : Pharmaceuticals and Biochemicals/Others

CAS NO : 454-31-9 EC NO : 207-223-4 MF : C7H11F3O MW : 168.1568 Specification : 99% min Packing : 25kg,50kg 200kg Product description : What is the chemical of Ethyl difluoroacetate? Appearance: Colorless transparent liquid with an irritating odor Assay:99%min by GC IR Identity: conform to standard HNMR: conform to standard carbon spectrum: conform to standard Water by K. F.:0.5% max or as per the customer’s request Loss on drying:0.5% max. or as per the customer’s request ============================================================================== Main applications: As a key intermediate in the synthesis of pharmaceuticals and pesticides, it is also used in esterification, cyclization, oxidation, and halogenation reactions in organic synthesis; Some literature mentions that it can be used as a solvent or functional reagent, but not as a bulk solvent. ============================================================================ Typical synthesis route: Tetrafluoroethylene and methanol are commonly used in industry to form methoxytetrafluoroethane, which is then catalytically cracked to produce difluoroacetyl fluoride and esterified with ethanol (EP0694523); Alternatively, difluoroacetic acid can be directly esterified with ethanol under acid catalysis (it should be noted that difluoroacetic acid itself is usually prepared by the chlorine/fluoroacetic acid route or electrochemical fluorination) Uses : 1.Pharmaceutical intermediates: used in cyclization, oxidation, and halogenation reactions in drug synthesis, as catalysts or reactants. 2. Pesticides and Organic Synthesis: Used as synthetic intermediates in the fields of pesticides and organic chemist Synonyms : Difluoroacetic acid ethyl ester;Ethyl difluoroacetic;3-(trifluoromethyl)cyclohexanol;Ethyl 2,2-difluoroacetate;Ethyl Difluoro Acetate;Ethyl difluorocetate;Ethyl Difluroacetate; Molecular Structure : 
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Ethyl difluoroacetate