China Suppliers > Tianjin Yuansu Chemical Reagent Co., LTD > 3-Dimethylamino-1-propanol
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3-Dimethylamino-1-propanol 3179-63-3
Category : Intermediates/Pharmaceutical intermediates
CAS NO : 3179-63-3 EC NO : 221-659-2 MF : C5H14NO MW : 104.1702 Specification : 99% min Packing : 25kg，50kg 200kg Product description : What is the chemical of 3-Dimethylamino-1-propanol ? Appearance: Light yellow or amber volatile liquid; Odor: No obvious odor or slight amine odor; Assay：99%min by GC ; IR Identity: conform to standard ; HNMR： conform to standard ; carbon spectrum: conform to standard ; Water by K. F.:0.5% max or as per the customer’s request ; Loss on drying:0.5% max. or as per the customer’s request ; boiling point: 163–164℃（760 mmHg）; ============================================================================= Main purpose Pharmaceutical raw materials: used for synthesizing central nervous system depressants such as chlorpromazine Industrial additives: Paper processing aids Gasoline additive Resin curing agent Chemical synthesis intermediates: can be used to prepare other nitrogen-containing compounds ============================================================================== synthetic route The main synthesis methods include: 1. Addition method of acrylic alcohol and dimethyl-amine In the presence of sodium hydroxide, propylene alcohol undergoes Michael addition reaction with dimethyl-amine, directly producing the target product 17. Reaction equation: \ceCH2=CHCH2OH+(CH3)2NH−>[NaOH](CH3)2NCH2CH2CH2OH\ceCH2=CHCH2OH+(CH3)2NH−>[NaOH](CH3)2NCH2CH2CH2OH 2. 3-bromo-1-propanol and dimethyl-amine substitution method 3-bromo-1-propanol reacts with dimethyl-amine with a yield of approximately 73%. 3. Acrolein reduction amination method Acrolein first reacts with dimethyl-amine to form imine, which is then reduced to obtain the product. However, there are many by-products and the yield is relatively low (about 13%) Uses : Pharmaceutical intermediates Synonyms : Dimethylaminopropanol;1-Dimethylamino-3-propanol;3-(Dimethlyamino)propanol;3-(Dimethylamino)-1-propanol;3-(Dimethylamino)propanol;3-(N,N-Dimethylamino)-1-propanol;3-(N,N-Dimethylamino)propanol;AI3-28566;Dimethylpropanolamine;N,N-Dimethyl-3-hydroxypropylamine;N,N-Dimethyl-gamma-aminopropanol;N,N-Dimethylpropanolamine;NSC 62086;gamma-(Dimethylamino)propanol;1-Propanol, 3-(dimethylamino)-;3-Dimethylaminopropan-1-ol;3-hydroxy-N,N-dimethylpropan-1-aminium; Molecular Structure : 
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3-Dimethylamino-1-propanol