China Suppliers > Tianjin Yuansu Chemical Reagent Co., LTD > 2-Hydroxypyridine
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- Region :China/Tianjin
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- Details for 2-Hydroxypyridine
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2-Hydroxypyridine 142-08-5
Category : Organic chemicals and Derivatives/Aroma compounds
CAS NO : 142-08-5 EC NO : 205-520-3;276-824-1 MF : C5H5NO MW : 95.0993 Specification : 99% min Packing : 25kg 50kg drum or bag Product description : What is the chemical of 2-Hydroxypyridine? Appearance: White to pale yellow crystals ; Solubility: Easily soluble in water (450 g/L, 20 ° C) and ethanol; Slightly soluble in benzene and ether; Almost insoluble in petroleum ether and hexane Assay: 99% min by HPLC ; IR Identity: conform to standard ; HNMR： conform to standard ; carbon spectrum: conform to standard ; Water by K. F.:0.5% max or as per the customer’s request ; Loss on drying:0.5% max. or as per the customer’s request ; Melting point: 105–107 °C; boiling point: 280-281 ° C (atmospheric pressure); ============================================================================= Purpose: Biological activity: As an endogenous metabolite, used for peptide synthesis Organic synthesis: As a pharmaceutical intermediate, for example, used in the synthesis of levetiracetam impurity reference substance Used for catalyzing the reaction of cyclic carbonates with alcohols to produce β - oxopropyl carbonates Can participate in [4+2] cycloaddition reactions due to its dual nucleophilic properties Industrial applications: Used for the synthesis of dyes (such as Reactive Yellow M-7G), pesticides, and polymer materials ============================================================================= Synthetic route The industrial preparation method is not detailed in the public information, but the following information is available for reference: Recrystallization purification: Pure product can be obtained by refluxing decolorization at 181-185 ° C/24 mmHg, followed by recrystallization in solvent systems such as ethanol, chloroform/ether, benzene/hexane, etc; It can also be combined with sublimation method Uses : As an endogenous metabolite, used for peptide synthesis Synonyms : 2(1H)-Pyridone;2-pyridone;2-Pyridinol; Pyridin-2-ol;2-Hydroxy Pyridine;pyridin-2(1H)-one; Molecular Structure : 
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2-Hydroxypyridine