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1,8-Dihydroxy Anthraquinone 117-10-2
Category : Dyestuffs and Pigments
CAS NO : 117-10-2 EC NO : 204-173-5 MF : C14H8O4 MW : 240.2109 Specification : 99% min Packing : 25kg 50kg drum or bag Product description : What is the chemical of 1,8-Dihydroxy Anthraquinone ? Appearance: Light yellow to orange brown crystalline powder； Assay:99%min by HPLC； IR Identity: conform to standard； HNMR： conform to standard； carbon spectrum: conform to standard； Water by K. F.:0.5% max or as per the customer’s request； Loss on drying:0.5% max. or as per the customer’s request； ========================================================================== 1,8-Dihydroxyanthraquinone has a wide range of applications, primarily focused in the fields of chemical industry, pharmaceuticals, and scientific research: Dyes and Pigment Intermediates: It serves as an important intermediate for synthesizing dyes, pigments, and printing inks, with its structure endowing it with excellent coloring properties. Pharmaceutical Intermediates: Used in the synthesis of various drugs, such as acting as impurities or synthetic precursors for drugs like Diclofenac Sodium and Estazolam (Istin). It was once used as a laxative (trade name Danthron) and is still employed in the research and development of anticancer and antifungal drugs. Chemical Reagents and Research: In organic synthesis, it functions as a reaction intermediate, used to compare acidity differences among anthraquinone compounds or as a candidate molecule for DNA gene probes. Natural Products and Standards: It is one of the active components in medicinal plants such as rhubarb and cassia seeds, often purified as a reference standard for quality testing of traditional Chinese medicines. Materials Science: Used as an intermediate for synthesizing polymers. ============================================================================== Synthesis Routes Industrially, the main methods for synthesizing 1,8-dihydroxyanthraquinone are as follows: - Anthraquinone Sulfonic Acid Alkali Fusion Method: Using anthraquinone as the raw material, it is first sulfonated to generate anthraquinone-1-sulfonic acid, then hydroxyl groups are introduced through a high-temperature alkali fusion reaction, ultimately obtaining 1,8-dihydroxyanthraquinone. - Nitroanthraquinone Reduction Hydrolysis Method: Nitroanthraquinone derivatives are obtained by nitration of anthraquinone, and the target product is prepared through subsequent reduction and hydrolysis reactions. - Oxidation Method: Under alkaline conditions, anthraquinone is directly oxidized using oxidants such as hydrogen peroxide, but this method has higher requirements for reaction condition control. These methods all need to be carried out under strictly controlled temperature and pH conditions to ensure the purity and yield of the product. (For reference only) Uses : 1,8-dihydroxyanthraquinone has a wide range of applications, mainly concentrated in the fields of chemical industry, medicine and scientific research Synonyms : Danthron;dantron;Chrysazine;1,8-dihydroxyanthracene-9,10-dione; Molecular Structure : 
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1,8-Dihydroxy Anthraquinone